Oxidative stress plays a role in sub-fertility by impacting egg quality. Antioxidants are compounds made in the body that help to mitigate oxidative stress. Coenzyme Q10 (CoQ10) is an antioxidant made endogenously by the body, and is also made synthetically, in the form of over-the-counter supplements. CoQ10 supplements, also known as ubiquinol is sometimes administered in the fertility context with the understanding it may reduce oxidative stress and therefore prevent the deterioration of egg quality. Current research suggests that it may increase clinical pregnancy rates but there are no high quality studies that suggest CoQ10/ubiquinol supplements improve live birth rate.

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Dr Anju Agarwal recommends 300mg daily for three months in the lead up to a stimulated cycle.